USTAR Center for Genetic Discovery

GENOMICS TOOLS

We produce algorithms, software tools, analysis pipelines, and data management systems for genomic big data.

DISEASE DISCOVERY

Our genomic medicine tools are used to discover, visualize, and report the genetic basis of disease.

INNOVATION

Our investigators lead cutting edge research programs that seek to break down computational barriers to genomics and genomic medicine.

ABOUT US

In 2014, the State of Utah Science Technology and Research (USTAR) initiative and the University of Utah Health Sciences Center established the USTAR Center for Genetic Discovery (UCGD) with the goal of leveraging Utah’s unique resources to create a computational genomics hub in Utah. We develop algorithms, software tools, analysis pipelines, and data management systems that enable researchers and clinicians to visualize and interpret genomic big data.

Genomic Medicine: A major focus of the UCGD is the integration of a patient’s genome data into health care. As “computational engine” for the Utah Genome Project and other large-scale personalized health initiatives, our tools enable the discovery of inherited disease risk factors. Our genomic medicine toolkit also includes software for tumor subclone monitoring, infectious disease diagnosis, data visualization, and clinical reporting.

Understanding Genomes: Together with our collaborators, UCGD investigators lead efforts to understand the structure and evolution of genomes. We develop better algorithms and methods to detect and report genetic variation, including structural variants, mobile elements, and regulatory elements. Our tools enable cost-effective and rapid annotation of genomes and genetic variation, supporting robust research programs in population, evolutionary, and agricultural genomics.

UCGD Staircase

UCGD Research Team Leaders

Mark Yandell

Mark Yandell

Principal Investigator

Every genome is a treasure trove of information about gene function, evolution, and disease. Our computational genomics tools are used to identify disease-causing variants in clinical settings, to understand the molecular basis of gene regulation and dysfunction, to annotate genomes, and to understand evolution.

Gabor Marth

Gabor Marth

Principal Investigator

My research group is building a web-based platform for interactive, real-time, analysis of genomic big data over the internet, with applications in genomic medicine and basic research. We also develop algorithms and tools to detect and annotate complex genomic structural variation.

Aaron Quinlan

Aaron Quinlan

Principal Investigator

Our lab marries genetics and genomics techniques with computer science, machine learning, and engineering to develop new ways of gaining insight into genome biology and the genetic basis of traits.

"We’re eliminating the need for expensive computational and hardware investments that before had limited genomic analysis to institutional-scale data centers."

Gabor Marth, UCGD Principal Investigator

By The Numbers

Genomics Software Tools Developed
Human Genomes Analyzed
Minutes To Analyze a Whole Human Genome
iphone6 devices to equal our computer cluster

@USTARGenetics TWITTER FEED

From the Blog

Get In Touch With Us

UCGD investigators welcome applications from qualified graduate students, postdocs, and software developers. If you’d like to work at the intersection of genomics and computer science, please get in touch.

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